The primary purpose of the study is to evaluate the effects of mild and moderate hepatic impairment on PK of tasurgratinib after a single dose administration.
Body mass index (BMI) between 18 to 40 kilogram per square meter (kg/m²).
For Cohorts A and B: stable hepatic impairment conforming to Child-Pugh classification A and B.
For Cohort C: healthy participants matched to participants with hepatic impairment with regard to age (+/-10 years), body weight (+/-20 percent [%]), race and gender, and as determined by no clinically significant deviation from normal in medical history, physical examination, electrocardiogram (ECG), and clinical laboratory determinations.
Following ocular disorders
Current evidence of Grade 2 or higher corneal disorder
Current evidence of active macular disorder (example, Age-related macular degeneration, central serous chorioretinal disease)
Known to be human immunodeficiency virus (HIV) positive at Screening.