Gum Arabic (GA), derived from Acacia trees, has shown potential benefits in metabolic, renal, and inflammatory conditions. This study explores the impact of GA on residual renal function in end-stage renal disease (ESRD) patients undergoing dialysis, as current evidence is limited.
Men and women ≥18 years of age with diagnosed ESRD and prescribed regular dialysis at least once a week, weekly at least for past two weeks.
For past two weeks including women of childbearing potential who are currently adopting any method of contraception or have completed the family and undergone sterilization procedures and women of non-childbearing potential.
Patients with residual renal function - Patients who produce a minimum of 200 ml of urine during a full day of collection (A full day collection: the patient discards the first urine sample on the day of collection then collects all urine for the entire day and night and collects the first urine sample of the next day) r on a non-dialysis long break day.
Able and willing to complete the whole period of the study (maximum of 266 days from enrolment).
Women of childbearing potential not adopting any methods of contraception, have not undergone sterilization.
Women Pregnant or lactating
Patients who plan to conceive (or for their partners to conceive) within 12 months of randomization.
Patient presenting with serum K+levels ≥ 6mmol/L based on the last two reports as per medical records.