The aim of this trial is to determine the potential effects and mechanisms of cannabinoid-induced pain relief in complex regional pain syndrome (CRPS). Multiple psychophysical approaches will be conducted in conjunction with psychological and inflammatory marker testing to determine if and how cannabinoids produce stabilized improvement in CRPS-related pain and comorbidities.
The trial consisted of a pre-treatment screening period, six-week treatment period and a two-week follow-up.
Provision of signed and dated informed consent form.
Are between 21-75 years old
Ability to communicate in English
Volunteers with no previous medical history (e.g., cardiac or pulmonary disease)
Fail cannabis screening
Active pulmonary disease
Allergy or past adverse effects or negative past experiences from cannabis
Positive urine drug test for THC, barbiturates, opioids, oxycodone, or methadone prior to study session 1 or session 2