The Relationship Between NLR and PONV and ESPB
Trial statusNot yet recruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18-80
SponsorQianfoshan Hospital
About this trial
This study aims to investigate whether preoperative NLR (Neutrophil-to-Lymphocyte Ratio) serves as a biomarker for PONV (Postoperative Nausea and Vomiting). It also examines the impact of erector spinae plane block on NLR and PONV. Furthermore, the research explores the effect of erector spinae plane block on postoperative pain relief in spinal surgery and its influence on the usage of opioid medications.
Eligibility criteria
Qualifiers
Patients undergoing elective posterior lumbar spine surgery in a prone position under general anesthesia.
ASA classification grades I to II.
Age between 18 and 80 years old.
Signed the informed consent for this study.
Disqualifiers
Preoperative blood transfusion.
Uncontrolled systemic diseases.
Patients with known uncontrolled systemic inflammatory diseases (e.g., rheumatoid arthritis, lupus, or active infections).
Gastrointestinal system disorders.
Trial design
Treatments tested in this trial
- Erector Spinae Plane Block
- 0.9% physiological saline (20ml) injection under ultrasound-guided Erector Spinae Plane Block (ESPB).
Treatment groups
220 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov