To Evaluate the Safety and Tolerability of Study Drug as a Third-line and Beyond Therapy for Recurrent or Metastatic Gastric Cancer

Trial statusNot yet recruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age19+
SponsorOnconic Therapeutics Inc.

About this trial

This study aims to evaluate the safety and tolerability of JPI-547 in combination with irinotecan as a third-line and beyond therapy for recurrent or metastatic gastric cancer

Eligibility criteria

Qualifiers

Patients with recurrent or metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma who have progressed after second-line therapy.

Those with Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1

Those with at least one measurable lesion in accordance with RECIST 1.1

Disqualifiers

Patients with a confirmed specific medical history or past surgical history

Patients who meet specific criteria regarding prior treatment

Patients with a history of specific drug administration

Patients with specific comorbidities.

Trial design

Treatments tested in this trial

  • JPI-547
  • Irinotecan (drug)

Treatment groups

49 Participants
are divided into 1 treatment group

Sponsors and collaborators