Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and Ecchymosis
Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18+
SponsorVanderbilt University Medical Center
About this trial
This study will be a prospective randomized study to evaluate the effect of tranexamic acid (TXA) use on intraoperative and postoperative outcomes among patients undergoing rhinoplasty by two Facial Plastic surgeons at Vanderbilt. Outcomes will include intra- and post-operative bleeding and postoperative bruising and swelling.
Eligibility criteria
Qualifiers
Adults at least 18 years of age who elect to undergo cosmetic or functional open primary rhinoplasty with osteotomies (repositioning the nasal bones) by Drs. Yang or Patel at VUMC.
No other facial plastics procedure nor sinus surgery performed simultaneously
Lack all the below
Disqualifiers
Known allergy to TXA (tranexamic acid)
Intracranial bleeding
Known defective color vision
History of venous or arterial thromboembolism
Trial design
Treatments tested in this trial
- Tranexamic acid
Treatment groups
60 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov