Use of Hyperpolarized 129Xe MR Lung Imaging in Adults for Calibration

Trial statusRecruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorChildren's Hospital Medical Center, Cincinnati

About this trial

The goal of this study is to evaluate the usefulness of hyperpolarized (HP) 129Xe (xenon) gas MRI for regional assessment of lung function in a normal population of adults for the purposes of obtaining optimal images through MRI.

Eligibility criteria

Qualifiers

Adults ages 18 years and older

Participant must be able to hold their breath for up to 16 seconds

Disqualifiers

History of heart defect

Pregnancy or positive pregnancy test

History of uncontrolled asthma defined for this study as requiring use of rescue inhaler ≥ 2 times in past month.

Symptoms of respiratory infection (loose or productive cough or wheeze), chest tightness, or sinus infection within past week.

Trial design

Treatments tested in this trial

  • Hyperpolarized 129 Xenon
  • MRI

Treatment groups

100 Participants
are divided into 1 treatment group