Using taVNS to Modulate Cardiovascular Function in Individuals With Neurologic Disease

Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18-80
SponsorUniversity of Alabama at Birmingham

About this trial

The purpose of this study is to find out whether a type of gentle nerve stimulation, called transcutaneous auricular Vagus Nerve Stimulation (taVNS), can help improve how the body regulates heart rate and blood pressure in people with Parkinson's Disease (PD). Problems with heart rate and blood pressure control are common and can make it harder for people to exercise or do daily activities. By using this non-invasive form of nerve stimulation and testing how it affects the body's natural responses, this study hopes to learn if taVNS could be a helpful tool to support physical therapy and improve overall function.

Eligibility criteria

Qualifiers

Diagnosis of idiopathic PD

Stable medication for at least 4 weeks prior to the study

Disqualifiers

Use of beta blockers

Sustained severe hypertension (>/= 180/110 mmHg while seated)

Significant uncontrolled cardiac arrhythmia

Unstable angina

Trial design

Treatments tested in this trial

  • transcutaneous auricular vagus nerve stimulation

Treatment groups

24 Participants
are divided into 2 treatment groups