Washed Microbiota Transplantation for Tourette's Syndrome
ConditionTourette Syndrome
Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age6-17
SponsorThe Second Hospital of Nanjing Medical University
About this trial
This study aimed to evaluate the efficacy of washed microbiota transplantation in the treatment of Tourette's syndrome (TS).
Eligibility criteria
Qualifiers
Patients were aged 6 to 17 years (inclusive);
Met the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition criteria for TS;
Had a Yale Global Tic Severity Scale-Total Tic Score (YGTSS-TTS) of at least 20 at screening and baseline.
Underwent WMT.
Disqualifiers
Complicated with certain brain disease, including tumor,injury,cerebrovascular disease;
Complicated with other severe disease, including cancers, organ failure, heart diseases;
Stereotypy associated with autism spectrum disorder;
With a confirmed diagnosis of psychiatric diseases, such as bipolar disorders; schizophrenia and major depressive disorders;
Trial design
Treatments tested in this trial
- Washed Microbiota Transplantation
Treatment groups
30 Participants
are divided into 1 treatment groupSponsors and collaborators
The Second Hospital of Nanjing Medical University
Lead sponsor
Nanjing Medical University
Collaborator
Source ClinicalTrials.gov