Wayne State Warriors Marijuana Clinical Research Program: Cannabinoid Adjunct to Prolonged Exposure & Recovery
Trial statusNot yet recruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18-60
SponsorWayne State University
About this trial
The overall strategy is to recruit veterans with PTSD who report minimal current cannabis use but are interested in or considering therapeutic cannabis to manage mental health symptoms (anxiety, depression, PTSD and/or suicidality). The information gained from this study could lead to the development of new treatments for persons who suffer from post-traumatic stress disorder and maintain better mental health.
Eligibility criteria
Qualifiers
Willing and able to consent to the study
Agree to comply with requirements and procedures
Veteran who has served in a branch of the US armed forces
Between ages 18-60
Disqualifiers
Pregnant, lactating or are a heterosexually active, pre-menopausal woman who is NOT using medically approved birth control (e.g., oral or depot contraception, contraceptive implant, IUD, condom/foam, sterilization, tubal ligation)
Current or past diagnosis of any bipolar or related disorder or schizophrenia spectrum and other psychotic disorder as determined by the SCID-5 or previous diagnosis by a licensed psychologist or psychiatrist
Determined to be at high risk for suicide requiring immediate intervention based on the C-SSRS and/or clinician judgment
Meet criteria for substance use disorder other than Cannabis Use Disorder or Alcohol (Mild or Moderate) or Nicotine Use Disorder, determined by the SCID-5
Trial design
Treatments tested in this trial
- Cannabidiol (CBD) only
- Placebo only
- Delta-9-tetrahydrocannabinol (THC) only
- THC:CBD 1:1
Treatment groups
280 Participants
are divided into 4 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov