18F-FDG PET/CT Guided Reduced-dose Radiotherapy for Nasopharyngeal Carcinoma

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-80
SponsorTaizhou Hospital

About this trial

The purpose of this study is to explore whether 18F-FDG PET/CT guided reduced-dose radiotherapy would maintain survival outcomes in nasopharyngeal carcinoma (NPC) patients.

Eligibility criteria

Qualifiers

Pathology confirmed nasopharyngeal squamous cell carcinoma.

Stage I-IVA(8thAJCC/UICC staging system).

Aged 18-80 years.

KPS≥70.

Disqualifiers

Past malignancies history (except for stage I non-melanoma skin cancer or cervical carcinoma in situ).

Age <18 or >80years.

Pregnancy or lactation.

History of previous radiotherapy (except for non-melanomatous skin cancers outside intended RT treatment volume).

Trial design

Treatments tested in this trial

  • Reduced dose
  • Conventional dose
  • Chemotherapy

Treatment groups

93 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Taizhou Hospital

Lead sponsor

Taizhou Enze Medical Center Group

Collaborator

Taizhou Cancer Hospital

Collaborator