About this trial
To evaluate the efficacy and safety of B007 in the Treatment of Primary Membranous Nephropathy
Eligibility criteria
Qualifiers
Subjects with primary membranous nephropathy pathologically confirmed by renal biopsy;
Subjects with glomerular filtration rate(eGFR) ≥ 45 mL/min/1.73 m2.
If taking Angiotensin converting enzyme inhibitors/angiotensin II receptor antagonists/sodium-glucose cotransporter 2 inhibitors/endothelin inhibitors, a stable dose within 4 weeks before randomization;
Subjects with 24-hour elevated urinary protein in accordance with the prescribed conditions;
Disqualifiers
Subjects with secondary membranous nephropathy or primary membranous nephropathy whose pathological reports suggest concomitant crescent bodies;
Subjects identified by the investigator as previously resistant to CD20 monoclonal antibody or cyclosporine;
Subjects who have received medication prescribed for membranous nephropathy;
Subjects with concomitant prescribed diseases;
Trial design
Treatments tested in this trial
- B007
- Cyclosporin Capsules
Treatment groups
Sponsors and collaborators
Shanghai Jiaolian Drug Research and Development Co., Ltd
Lead sponsor
Shanghai Pharmaceuticals Holding Co., Ltd
Collaborator