A Clinical Study of SCTB41 Combined With Docetaxel in Patients With Previously Treated Locally Advanced or Metastatic Non-Small Cell Lung Cancer(Phase II Study Ongoing)

Trial statusNot yet recruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorSinocelltech Ltd.

About this trial

This study aims to evaluate the safety and efficacy of SCTB41 combined with docetaxel in patients with previously treated non-small cell lung cancer. The Phase II part of this study is an open-label, multicenter clinical trial.

Eligibility criteria

Qualifiers

Voluntarily sign the informed consent form (ICF);

ECOG 0-1;

Survival duration more than 3 months;

Histologically or cytologically confirmed locally advanced (Stage IIIB/IIIC) or metastatic (Stage IV) non-small cell lung cancer (NSCLC) that is not amenable to complete surgical resection and cannot receive curative concurrent/sequential chemoradiotherapy;

Disqualifiers

Histologically or cytologically confirmed presence of small cell carcinoma components;

Prior treatment with docetaxel;

Symptomatic central nervous system (CNS) metastases;

Received the last dose of prior systemic anti-tumor therapy within 4 weeks before the first dose of study drug;

Trial design

Treatments tested in this trial

  • SCTB41
  • docetaxel

Treatment groups

90 Participants
are divided into 1 treatment group

Sponsors and collaborators