A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age60+
SponsorJanssen Research & Development, LLC

About this trial

The purpose of this study is to assess the long-term safety and tolerability after an intravitreal injection (a shot of medicine into the eye) of JNJ-81201887 administered in parent clinical studies.

Eligibility criteria

Qualifiers

Participants who were enrolled and received treatment with JNJ-81201887 or sham in a parent clinical study (81201887MDG2001, 81201887MDG1003)

Females (women of childbearing potential), male participants, and partners of male participants will not be required to use contraception in this LTE study

Must sign an informed consent form (ICF) indicating that participant understands the purpose of, and procedures required for, the study and is willing to participate in the study. The ICF may be signed by an impartial witness and/or legally designated representative depending on national/local regulations

Disqualifiers

There are no exclusion criteria for this LTE study

Trial design

Treatments tested in this trial

  • JNJ-81201887
  • Sham Procedure

Treatment groups

274 Participants
are divided into 3 treatment groups