A Reduced Dose of Cabergoline for Lactation Inhibition After Second-Trimester Abortion or Pregnancy Loss

Trial statusNot yet recruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexFemale
Age18-55
SponsorStanford University

About this trial

Most patients seeking abortion care or management of pregnancy loss in the second trimester will lactate, which can be physically and emotionally painful. The efficacy of a one-time dose of cabergoline has been previously demonstrated to prevent breast symptoms for these patients. This study seeks to determine if investigators can more precisely manage these patients with a reduced dose appropriate for the physiology of the second trimester, thereby reducing the medication cost and reducing or eliminating the uncomfortable medication side effects.

Eligibility criteria

Qualifiers

Pregnant people, ages 18 years or older

Intrauterine pregnancy between 16/0-25/6 weeks of gestation age (by ultrasound dating performed prior to or same day of enrollment visit)

Consented for an induced, elective abortion or undergoing management of fetal demise

English or Spanish speaking

Disqualifiers

Prior mastectomy (breast reduction or chest masculinization surgery acceptable)

Currently breastfeeding

Currently receiving dopamine agonist or antagonist therapy for other indication leg syndrome)

Contraindication to cabergoline (as per package insert)

Trial design

Treatments tested in this trial

  • Cabergoline

Treatment groups

36 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators