A Study of BL-B01D1 Combination Therapy in Patients With Metastatic Castration-resistant Prostate Cancer

Trial statusNot yet recruiting
Trial phasePhase 2, Phase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorSichuan Baili Pharmaceutical Co., Ltd.

About this trial

This study will first conduct a phase II clinical study, and on the basis of the phase II clinical study, subsequent clinical research will be carried out.

Eligibility criteria

Qualifiers

Voluntarily join this study and sign the informed consent form;

Age ≥ 18 years;

Expected survival time ≥ 3 months;

Unresectable metastatic castration-resistant prostate cancer;

Disqualifiers

Patients with metastatic castration-resistant prostate cancer who are suitable for radical local therapy;

Patients with non-prostatic acinar adenocarcinoma confirmed by histopathology or cytology, among others;

Patients who have previously received antibody-drug conjugates using topoisomerase I inhibitors as the toxin, among others;

Use of chemotherapy, targeted therapy, biological therapy, etc., within 4 weeks or 5 half-lives prior to study randomization;

Trial design

Treatments tested in this trial

  • BL-B01D1
  • Abiraterone
  • Olaparib

Treatment groups

180 Participants
are divided into 1 treatment group

Sponsors and collaborators

Sichuan Baili Pharmaceutical Co., Ltd.

Lead sponsor

Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Collaborator