A Study of BL-M14D1 in Combination With Atezolizumab in Patients With Extensive-stage Small Cell Lung Cancer

Trial statusNot yet recruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorSichuan Baili Pharmaceutical Co., Ltd.

About this trial

This Phase II study is a clinical study exploring the efficacy and safety of BL-M14D1 in combination with Atezolizumab in patients with extensive-stage small cell lung cancer.

Eligibility criteria

Qualifiers

Voluntarily sign the informed consent form and comply with the protocol requirements;

No gender restriction;

Age: ≥18 years;

Expected survival time ≥3 months;

Disqualifiers

Use of chemotherapy, biological therapy, immunotherapy, etc., within 4 weeks or 5 half-lives before the first dose;

Previous treatment with ADC drugs using topoisomerase I inhibitors as toxins;

Small cell carcinoma with non-small cell carcinoma components indicated by pathology must be excluded;

Use of immunomodulatory drugs within 2 weeks before the first dose of the study;

Trial design

Treatments tested in this trial

  • BL-M14D1
  • Atezolizumab

Treatment groups

36 Participants
are divided into 1 treatment group

Sponsors and collaborators

Sichuan Baili Pharmaceutical Co., Ltd.

Lead sponsor

Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Collaborator