About this trial
The goal of this clinical trial is to learn if Disitamab Vedotin combined with Toripalimab works to treat advanced HER2-positive extramammary Paget disease of the scrotum. It will also learn about the safety of this combination. The main questions it aims to answer are: Does this combination reduce tumor volume and delay disease progression? What medical problems do participants have when receving this combination? Participants will: Intravenous using this combination every 3 weeks until disease progression or intolerable adverse reactions occur. Visit the clinic once every 3 weeks for checkups and tests.
Eligibility criteria
Qualifiers
None
Disqualifiers
None
Trial design
Treatments tested in this trial
- Disitamab Vedotin combined with Toripalimab
Treatment groups
Sponsors and collaborators
Fujian Medical University Union Hospital
Lead sponsor
Zhejiang Tumor Hospital
Collaborator
Fujian Provincial Hospital
Collaborator
Zhangzhou Affiliated Hospital of Fujian Medical University
Collaborator
Quanzhou First Hospital
Collaborator
First Affiliated Hospital of Wenzhou Medical University
Collaborator