A Study of RC48-ADC Combined With JS001 for Advanced Extramammary Paget Disease of the Scrotum

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexMale
Age18-80
SponsorFujian Medical University Union Hospital

About this trial

The goal of this clinical trial is to learn if Disitamab Vedotin combined with Toripalimab works to treat advanced HER2-positive extramammary Paget disease of the scrotum. It will also learn about the safety of this combination. The main questions it aims to answer are: Does this combination reduce tumor volume and delay disease progression? What medical problems do participants have when receving this combination? Participants will: Intravenous using this combination every 3 weeks until disease progression or intolerable adverse reactions occur. Visit the clinic once every 3 weeks for checkups and tests.

Eligibility criteria

Qualifiers

None

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Disitamab Vedotin combined with Toripalimab

Treatment groups

20 Participants
are divided into 1 treatment group

Sponsors and collaborators

Fujian Medical University Union Hospital

Lead sponsor

Zhejiang Tumor Hospital

Collaborator

Fujian Provincial Hospital

Collaborator

Zhangzhou Affiliated Hospital of Fujian Medical University

Collaborator

Quanzhou First Hospital

Collaborator

First Affiliated Hospital of Wenzhou Medical University

Collaborator