A Study to Evaluate 608 in Patients With Non- Radiographic Axial Spondyloarthritis (Nr-axSpA)

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorSunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.

About this trial

This study will evaluate the effect and safety of 608 in patients with nr-axSpA.

Eligibility criteria

Qualifiers

Female and male patients at least 18 years of age at the time of screening.

Diagnosis of axial spondyloarthritis according to Ankylosing Spondylo Arthritis International Society (ASAS) axial spondyloarthritis criteria

Objective signs of inflammation (magnetic resonance imaging (MRI) or abnormal C-reactive protein)

Total back pain as measured by NRS ≥ 4 at baseline

Disqualifiers

Patients with other uncontrolled active inflammatory diseases.

Clinical laboratory tests and other tests that reveal abnormalities with clinical significance

Patients who have active Hepatitis B, Hepatitis C or HIV infections as determined by positive results at Screening.

History of cancer.

Trial design

Treatments tested in this trial

  • 608
  • 608
  • Placebo

Treatment groups

180 Participants
are divided into 3 treatment groups