A Study to Evaluate the Efficacy and Safety of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-65
SponsorAusper Biopharma Co., Ltd.

About this trial

This study is an open-label, multicenter phase II clinical study to evaluate the efficacy and safety of AHB-137 injection in participants with CHB previously treated with NA.

Eligibility criteria

Qualifiers

Voluntarily participate in the study and sign the informed consent form;

18-65 years of age (including boundary values) ;

Body mass index met the requirements;

Participants with CHB who are HBsAg or HBV DNA positive for at least 6 months;

Disqualifiers

Uncontrolled and stable clinically significant abnormalities other than a history of CHB infection;

Associated liver disease;

Any serious infection other than CHB infection requires intravenous anti-infective therapy;

HCV RNA positive, HIV antibody positive, syphilis positive;

Trial design

Treatments tested in this trial

  • AHB-137

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators