A Study to Evaluate the Efficacy and Safety of IN-207907 Injection in Elderly Patients With Sarcopenia

Trial statusNot yet recruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age65+
SponsorHK inno.N Corporation

About this trial

The goal of this clinical trial is to learn if intervention can treat sarcopenia in the elderly. Researchers will compare IN-207907 120 mg, 240 mg, 360 mg and placebo to see if SPPB score improves.

Eligibility criteria

Qualifiers

Subjects aged ≥ 65 years (for female subjects, those who are medically unable to become pregnant)

Subjects diagnosed with sarcopenia in accordance with the Korean Working Group on Sarcopenia (KWGS) guidelines

Subjects with a body weight of ≥ 35 kg and a body mass index (BMI) of ≥ 15 kg/m² and < 30 kg/m²

Subjects with a nutritional status screening score of ≥ 8 as assessed by the Mini Nutritional Assessment (MNA) questionnaire

Disqualifiers

Subjects with a history of diseases or surgical procedures that may affect physical activity or function

Subjects with underlying muscle disorders, including myopathy or muscular atrophy

Subjects with neuromuscular or neurological disorders

Subjects with uncontrolled diabetes mellitus, severe renal impairment, uncontrolled thyroid disorders, vitamin D deficiency, severe hepatic impairment, severe cardiac disease, uncontrolled hypertension, respiratory disorders

Trial design

Treatments tested in this trial

  • IN-207907 120 mg
  • IN-207907 240 mg
  • IN-207907 360 mg
  • Placebo

Treatment groups

100 Participants
are divided into 4 treatment groups

Locations

This trial has no locations

Sponsors and collaborators