About this trial
The goal of this clinical trial is to learn if intervention can treat sarcopenia in the elderly. Researchers will compare IN-207907 120 mg, 240 mg, 360 mg and placebo to see if SPPB score improves.
Eligibility criteria
Qualifiers
Subjects aged ≥ 65 years (for female subjects, those who are medically unable to become pregnant)
Subjects diagnosed with sarcopenia in accordance with the Korean Working Group on Sarcopenia (KWGS) guidelines
Subjects with a body weight of ≥ 35 kg and a body mass index (BMI) of ≥ 15 kg/m² and < 30 kg/m²
Subjects with a nutritional status screening score of ≥ 8 as assessed by the Mini Nutritional Assessment (MNA) questionnaire
Disqualifiers
Subjects with a history of diseases or surgical procedures that may affect physical activity or function
Subjects with underlying muscle disorders, including myopathy or muscular atrophy
Subjects with neuromuscular or neurological disorders
Subjects with uncontrolled diabetes mellitus, severe renal impairment, uncontrolled thyroid disorders, vitamin D deficiency, severe hepatic impairment, severe cardiac disease, uncontrolled hypertension, respiratory disorders
Trial design
Treatments tested in this trial
- IN-207907 120 mg
- IN-207907 240 mg
- IN-207907 360 mg
- Placebo