A Trial of SHR-7787 Injection Combined With Other Anti-tumor Drugs in Patients With Malignant Solid Tumors

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-75
SponsorShanghai Hengrui Pharmaceutical Co., Ltd.

About this trial

This study aims to evaluate the safety, tolerability and efficacy of SHR-7787 in combination with other anti-tumor drugs in patients with malignant solid tumors.

Eligibility criteria

Qualifiers

Ability to understand and voluntarily agrees to participate by giving written informed consent for the study;

Patients with histologically or cytologically confirmed unresectable solid tumors;

At least one measurable lesion was identified per RECIST 1.1;

Eastern Cooperative Oncology Group (ECOG) performance status (PS) score of 0 or 1;

Disqualifiers

Patients with known active central nervous system (CNS) metastases;

History of other malignancy within the past 5 years, with exceptions defined in the protocol;

Patients with uncontrolled cancer pain;

Patients with serious cardiovascular and/or cerebrovascular diseases;

Trial design

Treatments tested in this trial

  • SHR-7787 Injection
  • SHR-1316 Injection
  • SHR-4849 Injection
  • Etoposide injection
  • Carboplatin injection
  • Cisplatin injection
  • BP102 Injection

Treatment groups

400 Participants
are divided into 8 treatment groups

8

Treatment groups

See each treatment group below.