A Trial of SHR-A2102 With Other Antitumor Therapies in Advanced Solid Tumors

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-70
SponsorShanghai Hengrui Pharmaceutical Co., Ltd.

About this trial

The study is being conducted to evaluate the safety, tolerability and efficacy of SHR-A2102 with other antitumor therapies in advanced solid tumors to explore the reasonable dosage, safety and efficacy of SHR-A2102 for advanced solid tumors.

Eligibility criteria

Qualifiers

The age of signing the informed consent is 18 -70 years, regardless of gender.

At least one measurable lesion according to RECIST v1.1 criteria.

The ECOG score is 0 or 1.

Expected survival ≥12 weeks.

Disqualifiers

Inadequately treated central nervous system metastases or the presence of uncontrolled or symptomatic active central nervous system metastases.

Spinal cord compression not cured by surgery and/or radiotherapy.

Subjects with uncontrolled tumor-related pain.

Received antitumor therapy within 4 weeks before the start of the study.

Trial design

Treatments tested in this trial

  • SHR-A2102
  • Bevacizumab Injection
  • Adebelimab Injection
  • Ametinib Mesylate Tablets
  • Osimertinib Mesylate Tablets

Treatment groups

400 Participants
are divided into 1 treatment group