Absorbable Drug-Eluting Lacrimal Sac Stent for Recurrent Chronic Dacryocystitis

Trial statusNot yet recruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-65
SponsorBeijing Tongren Hospital

About this trial

This study aims to evaluate the safety and effectiveness of an absorbable lacrimal sac drug-eluting stent placed at the osteotomy site during endoscopic endonasal dacryocystorhinostomy (E-DCR) in patients with recurrent chronic dacryocystitis. The stent is composed of absorbable polymer mesh coated with mometasone furoate to reduce postoperative inflammation and adhesion, maintain ostium patency, and improve surgical outcomes. A total of 40 patients will be randomized 1:1 to receive either the absorbable stent or conventional packing with routine postoperative intranasal budesonide therapy.

Eligibility criteria

Qualifiers

Diagnosed chronic dacryocystitis

Disqualifiers

Nasal cavity structural disease: severe septal deviation, tumor, severe sinusitis

Trial design

Treatments tested in this trial

  • Absorbable Lacrimal Sac Drug-Eluting Stent
  • Conventional Ostium Packing with Budesonide Nasal Spray

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators