About this trial
The investigators believe that to effectively achieve malaria elimination in Rwanda, it is critical to target the human reservoirs of Plasmodium falciparum using local and readily available Artemisia tea. Asymptomatic infections detectable by PCR are important reservoirs because they often persist for months and harbor gametocytes, the parasite stage infectious to mosquitoes. Lessons learnt from this study will be of critical importance for health decision makers with regard to potential malaria control. MSc and PhD students will be trained and the impact of this research project will be enormous on the socioeconomic transformation of Rwanda.
Eligibility criteria
Qualifiers
Confirmed as asymptomatic reservoir of Plasmodium in the community or after completing standard malaria treatment.
Leave for at least one month in Rwanda for non-national
Be between 18 and 65 years of age, and in good general health.
Not taking any other malaria drug for prevention or treatment.
Disqualifiers
Have known hypersensitivity to any ingredients of the test treatment.
Have participated in any other malaria drug trial or device less than 14 days before.
History or presence of clinically significant medical, psychiatric, or emotional condition that would compromise the safety of the subject or adherence to the interventional requirements.
Be pregnant
Trial design
Treatments tested in this trial
- Artemisia afra or Annua 10g oral infusion/tea per day for 14 days