Adjuvant Chemoradiotherapy Followed by Zimberelimab for Locally Advanced Cervical Cancer.

Trial statusNot yet recruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexFemale
Age18-70
SponsorObstetrics & Gynecology Hospital of Fudan University

About this trial

Locally advanced cervical cancer (stage IB3, IIA2) patients with postoperative risk factors need better treatment. We initiated a clinical study to explore the effectiveness of adjuvant chemoradiotherapy followed by Zimberelimab for these patients.

Eligibility criteria

Qualifiers

Histologically confirmed cervical squamous cell carcinoma, cervical adenocarcinoma, or cervical adenosquamous carcinoma;

According to FIGO2018 staging, patients with locally advanced cervical cancer (IB3, IIA2) who require concurrent radiotherapy and chemotherapy;

Patients with radical surgery for cervical cancer;

Female patients: 18-70 years old;

Disqualifiers

Subjects have histological subtypes other than those permitted by inclusion criteria;

Severe hypersensitivity to cepalizumab and/or any of its excipients (≥ grade 3);

Participate in or have participated in other clinical trials within 4 weeks before enrollment;

Have received or will receive inactivated vaccine within 30 days prior to the first study treatment;

Trial design

Treatments tested in this trial

  • Zimberelimab
  • Platinum
  • radiotherapy

Treatment groups

24 Participants
are divided into 1 treatment group

Locations

This trial has no locations