An Exploratory Clinical Study of Statins for Improving Chemotherapy and Maintenance in Patients With Ovarian Cancer

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexFemale
Age18+
SponsorAnhui Provincial Cancer Hospital

About this trial

This study aims to evaluate the effect of statins combined with conventional chemotherapy and maintenance therapy on the prognosis of ovarian cancer patients, exploring its potential to improve survival rates and quality of life.

Eligibility criteria

Qualifiers

Participants must provide written informed consent before any trial procedures commence. The consent form must be documented and retained at the research center.

Female patients aged 18 years and older.

Patients diagnosed with ovarian cancer, fallopian tube cancer, or primary peritoneal cancer (collectively referred to as ovarian cancer) through open surgery, laparoscopic surgery, or core needle biopsy confirmed by pathology.

Patients who will require neoadjuvant chemotherapy followed by direct surgery, or direct surgical chemotherapy.

Disqualifiers

Are using other investigational drugs or participating in other clinical drug trials simultaneously;

Have used or are currently using any medications that interact with statins;

Have active cirrhosis, uncontrolled concurrent diseases, a history of chronic myopathy, active hepatitis, or unexplained persistent elevation of serum aminotransferases;

Are known to be allergic to statins, or any active or inactive components of drugs with similar chemical structures;

Trial design

Treatments tested in this trial

  • Statin
  • Sugar pill

Treatment groups

500 Participants
are divided into 2 treatment groups