Assessment of Volume-targeted Ventilation in Patients With Neuromuscular Disease

ConditionNeuromuscular Diseases

Trial statusRecruiting

Trial phasePhase 2

Trial typeInterventional

Biological sexAll

Age18-80

SponsorGuy's and St Thomas' NHS Foundation Trust

About this trial

Assessment of safety and efficacy of volume-targeted ventilation in patients with neuromuscular disease.

Eligibility criteria

Qualifiers

Slowly progressive neuromuscular disease

Established on fixed bi-level ventilation

Documented clinical respiratory stability by supervising clinician (no hospitalizations, respiratory infections or change to ventilator settings in preceding 6 weeks)

Disqualifiers

Rapidly progressive neuromuscular disease

Decompensated respiratory failure (pH < 7.35)

Pregnancy

Aged <18, >80

Trial design

Treatments tested in this trial

Volume-targeted non-invasive ventilation

Treatment groups

30 Participants

are divided into 1 treatment group

Sponsors and collaborators

Guy's and St Thomas' NHS Foundation Trust

Lead sponsor

Source ClinicalTrials.gov