Autologous Platelet-Rich Plasma Intra-ovarian Infusion in Poor Responders
Trial statusRecruiting
Trial phasePhase 2, Phase 3
Trial typeInterventional
Biological sexFemale
Age35-47
SponsorGenesis Athens Clinic
About this trial
Autologous PRP intra ovarian infusion may improve ovarian response, patients' hormonal profile as well as fresh embryo transfer (ET)-ICSI cycles' outcome in patients presenting with Poor Ovarian Response (POR).
Eligibility criteria
Qualifiers
Poor Ovarian Response according to Bologna Criteria (fulfilling 2 out of 3 of the following)
Age ≥ 40 years
AMH < 1.1 ng/ml OR AFC < 7
≤ 3 oocytes with a conventional stimulation protocol)
Disqualifiers
Any pathological disorder related to reproductive system anatomy
Cycle irregularities
Amenorrhea
Endometriosis
Trial design
Treatments tested in this trial
- PRP
- Placebo
Treatment groups
100 Participants
are divided into 2 treatment groupsSponsors and collaborators
Genesis Athens Clinic
Lead sponsor
National and Kapodistrian University of Athens
Collaborator
Source ClinicalTrials.gov