Health Trials

Autologous PRP Infusion May Restore Ovarian Function and May Promote Folliculogenesis in POI Patients

ConditionsMenopause, PrematureMenopause Related ConditionsMenopausal SyndromePremature Ovarian FailureOvarian Failure, Premature
Trial statusRecruiting
Trial phasePhase 2, Phase 3
Trial typeInterventional
Biological sexFemale
Age25-39
SponsorGenesis Athens Clinic

About this trial

Autologous PRP intra ovarian infusion may restore ovarian function, may promote folliculogenesis and may improve patients' hormonal profile in patients presenting with POI.

Eligibility criteria

Qualifiers

Age < 40 years, presenting with amenorrhea or menstrual cycle irregularities for at least four months, and elevated FSH levels >25 IU/L recorded on two occasions >4 weeks apart

Normal Karyotype: 46, XX

Discontinuation of any complementary/adjuvant treatment including hormone replacement, acupuncture, and botanotherapy, for at least three months prior to recruitment.

Willing to comply with study requirements

Disqualifiers

Any pathological disorder related to reproductive system anatomy

AMH > 8 pmol/L

Endometriosis

Adenomyosis

Trial design

Treatments tested in this trial

  • Autologous Platelet Rich Plasma
  • Placebo-Platelet Free Plasma

Treatment groups

100 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Genesis Athens Clinic

Lead sponsor

National and Kapodistrian University of Athens

Collaborator

Source ClinicalTrials.gov