CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-90
SponsorJason Sperry

About this trial

The CAlcium and VAsopressin following Injury Early Resuscitation (CAVALIER) Trial is a proposed 4 year, double-blind, mutli-center, prehospital and early in hospital phase randomized trial designed to determine the efficacy and safety of prehospital calcium and early in hospital vasopressin in patients at risk of hemorrhagic shock.

Eligibility criteria

Qualifiers

None

Disqualifiers

Wearing NO CAVALIER opt-out bracelet

Age > 90 or < 18 years of age

Isolated fall from standing injury mechanism

Known prisoner

Trial design

Treatments tested in this trial

  • Calcium Gluconate
  • Vasopressin
  • saline placebo

Treatment groups

1,050 Participants
are divided into 4 treatment groups

Sponsors and collaborators

Jason Sperry

Lead sponsor

University of Pittsburgh

Sponsor institution

United States Department of Defense

Collaborator