Cannabis' Impact on Alcohol Consumption
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age21-50
SponsorBrown University
About this trial
This study employs a repeated measures experimental design to examine the effect of THC-dominant dose of cannabis and CBD-dominant dose of cannabis, relative to placebo, on subsequent drinking in an alcohol choice task in which participants choose either to drink or receive monetary reinforcement for drinks not consumed. Cannabis will be administered simultaneously with an alcohol-priming dose or alcohol placebo.
The study will enroll up to 350 nontreatment-seeking heavy episodic alcohol drinkers who use cannabis weekly.
Eligibility criteria
Qualifiers
Age 21 to 50
English-speaking
cannabis smoking in past two months
heavy drinking in past two months
Disqualifiers
positive pregnancy test
nursing
positive urine toxicology screen for drugs other than cannabis
interest to quit or receive treatment for cannabis or alcohol use
Trial design
Treatments tested in this trial
- THC-dominant cannabis
- CBD-dominant cannabis
- Cannabis placebo
- Alcohol
- Alcohol placebo
Treatment groups
350 Participants
are divided into 5 treatment groupsSponsors and collaborators
Brown University
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Collaborator
Source ClinicalTrials.gov