Clinical Study on the First-line Treatment of Advanced Colorectal Cancer With Simultaneous Infusion of Levozolinate for Injection and 5-FU

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-75
SponsorChinese PLA General Hospital

About this trial

Phase II study of simultaneous infusion of levozolinate for injection and 5-FU as first-line treatment for advanced colorectal cancer

Eligibility criteria

Qualifiers

The subjects voluntarily joined this study and signed the informed consent form.

Age: 18 to 75 years old, gender not limited;

ECOG PS score: 0-2 points

Patients with unresectable or metastatic colorectal cancer confirmed by histology or cytology, where the primary tumor location and the status of RAS and BRAF are known;

Disqualifiers

Those who have been confirmed to be allergic to the test drug and/or its excipients;

Those with contraindications to chemotherapy;

Colorectal cancer patients with MSI-H or dMMR;

Pregnant or lactating women;

Trial design

Treatments tested in this trial

  • mFOLFOX/FOLFIRI ( Standard Chemotherapy)

Treatment groups

583 Participants
are divided into 2 treatment groups

Sponsors and collaborators