Clinical Trial of TQB2825 Injection Combined With Chemotherapy in Subjects With Diffuse Large B-cell Lymphoma

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorShanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd.

About this trial

The purpose of this study is to assess the preliminary efficacy of TQB2825 in combination with chemotherapy in subjects with diffuse large B-cell lymphoma.

Eligibility criteria

Qualifiers

The subjects voluntarily participate in this study, sign the informed consent form, and have good compliance;

Age ≥18 years (calculated from the date of informed consent);

Eastern Cooperative Oncology Group (ECOG) score 0 ~ 2 points;

Expected survival greater than 12 weeks;

Disqualifiers

Subjects who had or currently had other malignant tumors within 5 years prior to the first dose;

Previous or current involvement or suspected involvement of the central nervous system by lymphoma;

Failure to recover from adverse reactions to Common Terminology Criteria for Adverse Events version 5.0 (CTCAEv5.0) criteria ≤ grade 1 from previous treatment;

previous use of other antibody drugs targeting CD3 and CD20 at the same time;

Trial design

Treatments tested in this trial

  • TQB2825 Injection + Gemcitabine Hydrochloride for Injection + Oxaliplatin for Injection

Treatment groups

55 Participants
are divided into 1 treatment group