Randomized, controlled, double-blind, three-arm clinical trial in which 75 women will be randomized to treatment with metformin, 75 women to treatment with placebo and 50 women to the observation group. The medical intervention will last 24 weeks (6 months). Women with confirmed idiopathic infertility, in whom infertility factors have been excluded during full diagnostics, will be included in the study
Age 18-45
No pregnancy for a minimum of 12 months prior to screening.
Diagnosed with idiopathic infertility.
No use of hormone therapy 30 days before screening.
Positive pregnancy test result.
Patients diagnosed with another factor of infertility.
Patients with type I or II diabetes.
Patients taking metformin or other hypoglycaemic drugs in the last 4 weeks before screening.
Medical University of Bialystok
Lead sponsor
Medical Research Agency, Poland
Collaborator