Does intraductal administration of antibiotics during endoscopic retrograde cholangiopancreatography (ERCP), in addition to standard systemic antibiotic therapy, improve clinical outcomes in patients with acute cholangitis compared with standard systemic antibiotic therapy alone?
The patients diagnosed with mild and moderate acute cholangitis based on TG 18
Planned for ERCP within 48 hours
18 years old and above
Severe acute cholangitis
History of antibiotic hypersensitivity
Receiving cancer chemotherapy, steroids, or immunosuppressive agents
Concomitant infections
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Malaysia