Comparative Study for Facial Scar Remodeling Using Fractional Carbon Dioxide Laser Combined With PDRN Versus Fractional CO₂ Laser

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-50
SponsorMisr University for Science and Technology

About this trial

Facial scars are frequently deemed unpleasant and can profoundly impact a patient's psychological health. This study compares the effectiveness, safety, and capacity to speed up scar healing in the maxillofacial region between fractional carbon dioxide (CO₂) laser therapy alone and polydeoxyribonucleotide (PDRN) combined with CO₂ laser therapy.

Eligibility criteria

Qualifiers

Age Limitations: Participants must be between 18 and 50 years of age.

Recently cut wounds or surgical scars from about (1-6 months).

Consent to Participate: Willingness to provide informed consent and engage in all aspects of the study.

Disqualifiers

Pregnancy or breastfeeding at the time of study.

Known allergy to PDRN.

Isotretinoin.

Anticancer drugs.

Trial design

Treatments tested in this trial

  • Polydeoxyribonucleotide
  • Fractional CO2 laser assisted PDT

Treatment groups

36 Participants
are divided into 2 treatment groups