Comparison of Submucosal Dexamethasone and Methylprednisolone in Postoperative Sequelae of Parasymphsis Fractures

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-40
SponsorNishtar Medical University

About this trial

The rationale of the current research is to address the limitation of existing knowledge as it is not clear which of the two drugs (Dexamethasone or Methylprednisolone) is more effective in reduction of postoperative sequelae in patient with mandibular parasymphysis fracture. This study fills the gap by providing sound evidence on the preferred steroid option to help clinicians have more data to make decisions and improve patients' health. The result of this research will then be added to the evidence-based protocols for the treatment of parasymphysis fractures.

Eligibility criteria

Qualifiers

Patients aged 18 to 40.

Both Gender.

Fracture less than a week old.

Isolated mandibular parasymphysis fractures.

Disqualifiers

1. Immunocompromised patients (due to increased risk of infection and complications).

Trial design

Treatments tested in this trial

  • Dexamethasone
  • Methylprednisolone (Corticosteroid)

Treatment groups

72 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Nishtar Medical University

Lead sponsor

University of Health Sciences Lahore

Sponsor institution