"Dexa vs Dexmedetomidine With Bupivacaine in TAP Block for Laparotomy Analgesia

Trial statusRecruiting
Trial phasePhase 2, Phase 3
Trial typeInterventional
Biological sexAll
Age25-65
SponsorSahiwal medical college sahiwal

About this trial

Transversus abdominis plane block is a regional anesthetic technique which blocks the abdominal neural afferents by introducing local anesthetic into the neuro-fascial plane between the internal oblique and the transversus abdominis muscle and gives analgesia from the skin to parietal peritoneum. There are studies showing evidence of improved post operative analgesia with addition of adjuvants such as dexmedetomidine or dexamethasone in comparison with plane local anesthesia in terms of time to rescue analgesia and the overall quantity of analgesic used post operatively.

Eligibility criteria

Qualifiers

Patients undergoing laparotomy.

Patients aged 25 to 65 years.

Both genders.

Patients with ASA Class I, II.

Disqualifiers

Patients who do not give consent.

Patients with Comorbidities like DM, HTN, CKD, CLD.

Patients with bleeding disorders.

Infection at site of injection.

Trial design

Treatments tested in this trial

  • Bupivacaine Hcl 0.25% Inj_#1
  • Bupivacaine Hcl 0.25% Inj_#2

Treatment groups

96 Participants
are divided into 2 treatment groups