Drug-Induced Sleep Endoscopy for Upper Airway Evaluation in Obstructive Sleep Apnea

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of California, Los Angeles

About this trial

Prospective, interventional cohort study of drug-induced sleep endoscopy (DISE) to evaluate the upper airway in a cohort of obstructive sleep apnea (OSA) surgical patients. This study has investigated the reliability of this technique, demonstrating moderate-substantial interrater and test-retest reliability. This research has also compared DISE findings to those of the lateral cephalogram X-ray and examined DISE findings in individuals who have not responded to previous sleep apnea surgery. These papers have been published and available through PubMed. Additional research is ongoing, with examination of DISE findings, comparison to other evaluation techniques, and the association between DISE findings and surgical outcomes.

Eligibility criteria

Qualifiers

Adult patients with OSA considering surgical treatment

Disqualifiers

Minors

Pregnant women

Patients unable to provide informed consent in English themselves

Prisoners

Trial design

Treatments tested in this trial

  • Propofol sedation

Treatment groups

800 Participants
are divided into 1 treatment group

Sponsors and collaborators

University of California, Los Angeles

Lead sponsor

National Institutes of Health (NIH)

Collaborator

American Academy of Otolaryngology-Head and Neck Surgery Foundation

Collaborator