Early-stage Trial to Determine a Safe and Effective Dose for Ratutrelvir in Patients With Mild to Moderate COVID-19

ConditionCOVID - 19
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorTraws Pharma, Inc.

About this trial

This is an Early-stage Clinical Trial to Determine a Safe and Effective Dose for Ratutrelvir in Patients With Mild to Moderate COVID-19. It will also learn about the safety of drug Ratutrelvir. Participants will take a study drug as well as a standard therapy. A descriptive statistics will be used to present the study results.

Eligibility criteria

Qualifiers

Confirmed SARS-CoV-2 infection for 120 h prior to randomization.

Initial onset of signs/symptoms attributable to COVID-19 within 5 days prior to randomization.

Disqualifiers

History, current need for hospitalization or anticipated need for hospitalization for the medical treatment of COVID-19.

Urgent or expected need for nasal high-flow oxygen therapy or positive pressure ventilation, invasive mechanical ventilation or ECMO.

Known medical history of active liver disease .

Receiving dialysis or history of moderate to severe renal impairment.

Trial design

Treatments tested in this trial

  • Ratutrelvir (83-0060) non-randomised
  • Paxlovid
  • Ratutrelvir (83-0060)

Treatment groups

90 Participants
are divided into 3 treatment groups

Sponsors and collaborators