About this trial
Intranasal nasal steroid sprays are the mainstay of treatment for chronic Eustachian tube dysfunction despite having little supportive evidence in the literature. A novel, commercially available nasal spray delivery system is available now for fluticasone that improves its delivery to the nasopharynx. The hypothesis of this study is that fluticasone using the novel spray system is effective for Eustachian tube dysfunction (ETD).
Eligibility criteria
Qualifiers
Age greater than or equal to 18 years old, <80 years old
Symptoms in one or both ears > 3 months AND
ETDQ-7 score >14.5 AND
Type B, C, or As tympanometry
Disqualifiers
Age <18 years old
Known history of otologic surgery (excluding myringotomy or myringotomy tubes)
Use of any additional intranasal medication
Tympanic membrane perforation
Trial design
Treatments tested in this trial
- Fluticasone Propionate 93 MCG/1 ACTUATION Nasal Spray
- Placebo Nasal Spray
Treatment groups
Sponsors and collaborators
Cedars-Sinai Medical Center
Lead sponsor
Sacramento Ear, Nose & Throat
Collaborator
Ochsner Health System
Collaborator
Indiana University
Collaborator