Treatment of Adult Patients with Newly Diagnosed Langerhans Cell Histiocytosis (LCH) Using a Low-Dose Cytarabine Combined with Thalidomide Regimen.
Clearly diagnose and treat adult patients with multisystem or single-system multifocal LCH;
Aged between 18 and 70 years;
Multisystem involvement or single-system multifocal disease;
No prior systemic treatment (patients who have only received local radiotherapy or surgery may be enrolled);
Patients with LCH involving the central nervous system;
Single-system single-lesion LCH;
Subjects who have undergone major surgery within 4 weeks prior to the first dose in the study;
Subjects who have received radiotherapy within 4 weeks prior to the first dose in the study; subjects with a history of myocardial infarction within the past year;