Efficacy and Speed of Response of Lebrikizumab in High-Burden Prurigo Nodularis Patients

Trial statusNot yet recruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-80
SponsorUniversity of Maryland, Baltimore

About this trial

The purpose of this study is to evaluate the effectiveness of lebrikizumab in treating adults with moderate-to-severe Prurigo Nodularis (PN).

Eligibility criteria

Qualifiers

Age 18-80

Diagnosis of Prurigo Nodularis (PN) for at least 1 year

Active PN with moderate-to-severe itch, several nodules, and presence of nodules in more than one part of the body

Women of childbearing potential must agree to remain abstinent or use a highly effective contraceptive method during treatment and for at least 18 weeks after the last dose of study drug

Disqualifiers

Prior participation in a lebrikizumab study

History of anaphylaxis

History of or active HIV

Active hepatitis or known liver cirrhosis

Trial design

Treatments tested in this trial

  • Lebrikizumab

Treatment groups

15 Participants
are divided into 1 treatment group

Sponsors and collaborators

University of Maryland, Baltimore

Lead sponsor

Eli Lilly and Company

Collaborator