Efficacy of Montelukast in Preventing Transaminase Elevation in Adult Dengue Patients
Trial statusRecruiting
Trial phasePhase 2, Phase 3
Trial typeInterventional
Biological sexAll
Age20+
SponsorPhramongkutklao College of Medicine and Hospital
About this trial
The goal of this clinical trial is to learn if drug montelukast works to treat dengue in adults. It will also learn about the safety of drug montelukast . The main questions it aims to answer are:
Does drug montelukast lower the incidence of liver enzyme elevations in participants ? What medical problems do participants have when taking drug montelukast ?
Eligibility criteria
Qualifiers
Patient age >18 years
Dengue infection diagnosed by NS1 antigen, or polymerase chain reaction
Admitted to the hospital
Written informed consent from patient or attending relative able to and willing to give informed consent
Disqualifiers
Other possible cause of fever other than dengue infection
Pregnancy
Unable to take medication
Aminotransferase level above 150 U/l
Trial design
Treatments tested in this trial
- Montelukast
- Montelukast Placebo
Treatment groups
82 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov