About this trial
This study is a single-arm, prospective, open-label observational clinical study to evaluate the efficacy and safety of Bevacizumab combined with Oxaliplatin and TAS-102 in patients with advanced unresectable rectal cancer.
Eligibility criteria
Qualifiers
age: ≥18 years and ≤75 years;
ECOG score 0~1 points;
advanced colorectal cancer patients
According to RECIST1.1 criteria, there is at least one measurable target lesion, and tumor imaging evaluation is performed within 28 days before the first dose;
Disqualifiers
Patients who have received first-line standard therapy;
Previous antitumor therapy or radiation therapy for any malignant tumor;
concurrently receiving anti-tumor therapy in other clinical trials, including endocrine therapy, bisphosphonate therapy, or immunotherapy;
Has undergone major surgical procedures not related to colorectal cancer within 4 weeks prior to enrollment, or the patient has not fully recovered from such surgical procedures;
Trial design
Treatments tested in this trial
- Bevacizumab combined with Oxaliplatin and TAS-102