This study aims to explore the safety and efficacy of eliminating the planning target volume (PTV) margins based on MRI-guided adaptive stereotactic radiotherapy for non-small cell lung cancer (NSCLC) patients with brain metastasis.
Aged 18-75 years
Histologically or cytologically confirmed non-small cell lung cancer
1-10 metastases on contrast-enhanced MRI
Radiotherapy for extracranial lesions is permitted
Small cell carcinoma of lung
Intracranial metastases needed surgical decompression
Patients with contraindications for MRI
Previous radiotherapy or excision for intracranial metastases