A Phase 2a, Multicenter, Randomized, Open-label, Active Drug-controlled Trial to Evaluate the Efficacy and Safety of JMKX003002 in End-Stage Renal Disease Patients on Hemodialysis with Hyperphosphatemia
Able to understand the procedures of this trial and provide written informed consent voluntarily;
Age ≥ 18 years, male or female;
On a stable hemodialysis regimen at a frequency of two or three times per week for at least 12 weeks prior to the screening visit;
Serum phosphorus within the trial-required range.
Any history of inflammatory bowel disease or diarrheal irritable bowel syndrome;
Pregnant or breastfeeding;
Any history of a parathyroid intervention;
Diarrhea or loose stools occurred within 1 week prior to randomization.