The purpose of this study is to see if the study drug CIR-0602K will improve glucose time-in-range and/or lower total daily insulin dose in people with type 1 diabetes who are using closed-loop automated insulin delivery. Researchers will compare CIR-0602K to a placebo (a look-alike substance that contains no drug) to see if it achieves the investigational endpoints. If the study results show that the drug works to increase time-in-range and lower insulin doses, this will lead to further studies which may then make the drug available to the public.
Provision of signed and dated informed consent form
Stated willingness to comply with all study procedures and availability for the duration of the study
History of type 1 diabetes for at least one year
Age 18-45 years
Current Pregnancy or currently breastfeeding.
History of smoking tobacco products within the last two years.
History of alcohol abuse or illicit drug abuse within 6 months of screening.
Known history of human immunodeficiency virus (HIV).