About this trial
The goal of this clinical trial is to learn if Obicetrapib works to change antioxidant levels in HDL and plasma, as well as retinal tissue. The main questions it aims to answer are:
Do Obicetrapib effect absorption of antioxidants in a person's blood or their eye tissue? Researchers will compare Obicetrapib to a placebo (a look-alike substance that contains no drug) to see if Obicetrapib helps improve a person's ability to absorb antioxidants.
Participants will:
Take Obicetrapib or a placebo every day for 4 months Visit the clinic once every 8 weeks for checkups and tests Have their blood taken and their eyes checked to measure antioxidant levels
Eligibility criteria
Qualifiers
Visual acuity > 20/60 in both eyes with or without corrective lenses
Disqualifiers
Type 2 diabetes
Active liver disease
Any clinically significant macular pathology
Trial design
Treatments tested in this trial
- Obicetrapib 10mg
- Placebo
Treatment groups
Sponsors and collaborators
NewAmsterdam Pharma
Lead sponsor
MB Clinical Research and Consulting LLC
Collaborator